PROGNOSTIC SIGNIFICANCE OF GENE SIGNATURE OF TERTIARY LYMPHOID STRUCTURES IN PATIENTS WITH LUNG ADENOCARCINOMA

Prognostic Significance of Gene Signature of Tertiary Lymphoid Structures in Patients With Lung Adenocarcinoma

BackgroundLung adenocarcinoma (LUAD) is a highly mortal cancer.Tertiary lymphoid structures (TLS) are ectopic lymphoid organs with similar morphological and molecular characters to secondary lymphoid organ.The aim of this study is to investigate the prognostic effect of a gene signature associated with TLSs, including B-cell-specific genes.MethodsC

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HAART and the liver: friend or foe?

Abstract The overall effect of HAART on the liver is the result of the balance between hepatotoxicity and the consequences of immunoreconstitution on the evolution of HIV-associated liver diseases, particularly viral hepatitis.HAART may lead to the emergence of acute toxic hepatitis, steatosis, steatohepatitis, liver fibrosis, Bowden Cable and nonc

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Phylogenomic Analyses Clarify True Species within the Butterfly Genus Speyeria despite Evidence of a Recent Adaptive Radiation

When confronted with an adaptive radiation, considerable evidence Makeup Bag is needed to resolve the evolutionary relationships of these closely related lineages.The North American genus Speyeria is one especially challenging radiation of butterflies due to potential signs of incomplete lineage sorting, ongoing hybridization, and similar morpholog

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